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The most common type of virus leading to rhinitis is ________.


A) coronavirus
B) adenovirus
C) rhinovirus
D) herpes simplex virus
E) retrovirus

F) A) and B)
G) A) and C)

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A diagnosis of tuberculosis involves a(n) ________.


A) chest X-ray
B) acid-fast stain of sputum
C) sputum culture
D) tuberculin skin test
E) All of the choices are correct.

F) B) and E)
G) A) and B)

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Influenza vaccines include all the following except ________.


A) an inactivated dead virus
B) the incorporation of usually three different strains
C) an attenuated nasal drops vaccine
D) the ability to provide lifelong immunity
E) an overall effectiveness of 70%−90%

F) A) and B)
G) C) and D)

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Antigenic drift differs from antigenic shift in that antigenic drift reflects the exchange of RNA strands between different virus strains within a common host cell, whereas antigenic shift is the gradual mutation over time of the glycoproteins on the viral envelope that bind to immune cells.

A) True
B) False

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Which of the following pairs of defense mechanisms is mismatched?


A) Complement activation - third line of defense
B) Ciliated epithelium - first line of defense
C) Secretory IgA - third line of defense
D) Antimicrobial peptides - second line of defense
E) Coughing - first line of defense

F) B) and C)
G) B) and D)

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An induration of less than 5 mm in the Mantoux test is negative for TB.

A) True
B) False

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The rapid microbial analysis is negative for group A Streptococcus and reveals the presence of only normal biota in the patient specimen. Based upon this information, all of the following microbes can be ruled out in the diagnosis except ________.


A) Streptococcus pyogenes
B) Staphylococcus aureus
C) Haemophilus influenzae
D) Influenza A

E) A) and B)
F) B) and C)

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The patient's clinical condition deteriorates rapidly. Even without laboratory confirmation of the pathogen, the provider orders which course of treatment?


A) Administration of rimantadine to treat the patient's suspected influenza
B) Administration of trimethoprim-sulfamethoxazole to treat the patient's suspected PCP
C) Administration of ciprofloxacin to treat the patient's suspected pulmonary anthrax
D) Administration of antitoxin to treat the patient's suspected diphtheria

E) C) and D)
F) A) and B)

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Which disease involves transmission by aerosolized water from whirlpool spas, air conditioners, cooling towers, and supermarket vegetable misters?


A) Legionellosis
B) Pertussis
C) Brucellosis
D) Plague
E) Traveler's diarrhea

F) A) and C)
G) A) and B)

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Legionellosis is a zoonosis.

A) True
B) False

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Which of the following is not a virulence factor of Bordetella pertussis?


A) Endotoxin
B) Tracheal cytotoxin
C) M protein
D) Pertussis toxin
E) Filamentous hemagglutinin

F) A) and E)
G) A) and B)

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Rheumatic fever is caused by ________.


A) a primary streptococcal infection with Streptococcus pyogenes
B) a combination of infection with Streptococcus pyogenes and the rheumatic fever virus
C) a secondary streptococcal infection with a different type of streptococcus
D) an immunological cross-reaction in which anti-streptococcal antibodies target the heart
E) both a primary viral infection and a secondary streptococcal infection

F) A) and B)
G) B) and D)

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The major virulence factor of Corynebacterium diphtheriae that causes serious systemic effects is ________.


A) its capsules
B) metachromatic granules
C) an exotoxin
D) endospores
E) an endotoxin

F) D) and E)
G) A) and C)

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Tuberculin skin testing ________.


A) injects PPD intradermally
B) uses a purified protein filtrate of Mycobacterium tuberculosis
C) will be positive if the person has had previous exposure to TB
D) will be positive if the person has active TB
E) All of the choices are correct.

F) C) and D)
G) B) and E)

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All of the following pertain to tuberculosis except ________.


A) live bacilli can remain dormant in the lungs and reactivate later in life
B) symptoms of active TB include low-grade fever, coughing, fatigue, weight loss, and night sweats
C) lung infection can disseminate to many other organs in extrapulmonary TB
D) the BCG vaccine is used in other countries
E) antimicrobials cannot treat and cure tuberculosis

F) A) and B)
G) A) and C)

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Streptococcal pharyngitis involves all of the following except ________.


A) a purulent exudate over the tonsils
B) it can lead to scarlet fever if it is an erythrogenic toxin-producing strain
C) it can lead to serious sequelae
D) it is viral in origin
E) it causes difficulty in swallowing and fever

F) C) and E)
G) All of the above

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Pertussis outbreaks still occur in the United States.

A) True
B) False

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Which of the following is not true of influenza?


A) It has glycoprotein spikes of hemagglutinin (H) and neuraminidase (N) .
B) Antigenic drift which changes the antigens to reduce immune recognition.
C) Antigenic shift causes changes in the RNA strands.
D) Symptoms are very similar to the common cold.
E) The virus can infect both humans and swine.

F) C) and D)
G) B) and D)

Correct Answer

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The enzyme associated with the influenza virus that hydrolyzes the protective mucous coating of the respiratory tract is ________.


A) catalase
B) reverse transcriptase
C) hyaluronidase
D) neuraminidase
E) kinase

F) C) and D)
G) A) and B)

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The highest incidence of histoplasmosis in the United States occurs in the ________.


A) Southeast
B) Southwest
C) East and Midwest
D) Northeast
E) Rocky Mountains

F) B) and D)
G) B) and E)

Correct Answer

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