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Prions are


A) strands of nucleic acids encased in a protein coat.
B) viral nucleic acids integrated into the host chromosomes.
C) viral-infected cells.
D) infectious proteins with no associated nucleic acid.

E) B) and D)
F) C) and D)

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The specific white blood cells that HIV attaches to are the ____________ cells.


A) CD4+
B) gp120 -T
C) CCR5-T
D) CXCR4-T

E) A) and B)
F) All of the above

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Can a virus be killed?


A) Yes, destroying its genome kills it.
B) No, viruses are capable of self-assembly and cannot be permanently killed.
C) Yes, separating the genes from the capsid kills it.
D) No, viruses are non-living and cannot die.

E) All of the above
F) A) and D)

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A scientist is studying the lysogenic cycle of the lambda 1 phage of Escherichia coli.This means that she is investigating


A) the integration and stabilizing of the lambda 1 phase into a host cell's genome.
B) the integration of the bacteria's genome with the viral genome outside of the bacteria's cell wall.
C) the integration of the viral genome into the ribosomes present in the bacteria to direct protein synthesis for the capsid formation.
D) the integration and stabilizing of a virus into its capsid, which provides protection until conditions are better for reproduction.

E) None of the above
F) All of the above

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Recently a class of infectious proteins with no associated nucleic acid have been identified.They are referred to as


A) bacteriophages.
B) latent viruses.
C) viroids.
D) prions.

E) None of the above
F) C) and D)

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Which of the following statements about TSEs (transmissible spongiform encephalopathies) is false?


A) TSEs include scrapie in sheep, mad cow disease, chronic wasting disease in deer and elk, and kuru and variant Creutzfeldt-Jakob disease in humans.
B) The incidence of Creutzfeldt-Jakob disease in humans increased after an outbreak of mad cow disease in England, suggesting that mad cow disease may be transmitted to humans.
C) Viroids are the likely cause of TSEs.
D) TSEs do not seem to be affected by treatments that would eliminate nucleic acid-based diseases.

E) B) and C)
F) A) and D)

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Viruses are self-replicating but the replication is much faster in a host cell.

A) True
B) False

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The switch from a lysogenic prophage to a lytic cycle is called


A) transformation.
B) induction.
C) latency.
D) phage conversion.

E) All of the above
F) A) and B)

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Which of the following is a unique feature of viruses that separates them from bacteria?


A) They are generally smaller.
B) They are often highly toxic.
C) They lack proteins.
D) They have different nucleotides in their hereditary material.

E) A) and B)
F) B) and C)

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Diseases such as scrapie in sheep, "mad cow" disease in cattle, and Creutzfeldt-Jakob disease in humans are known as


A) viroids.
B) viruses.
C) retroviruses.
D) TSEs (transmissible spongiform encephalopathies) .

E) A) and B)
F) A) and C)

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