Question 1

Given that these two gene loci are very closely linked, the phenotypic ratio in the F2 generation should be closest to

Accepted Answer

A)  1 brown eye, heavy wing veins: 2 red eye, thin wing veins: 1 brown eye, thin wing veins
B)  1 brown eye, thin wing veins: 2 red eye, thin wing veins: 1 red eye, heavy wing veins
C)  3 red eye, thin wing veins: 1 brown eye, heavy wing veins
D)  1 brown eye: 1 red eye: 1 heavy wing veins: 1 thin wing veinsE) B) and D)
F) All of the above

Question 2

In Morgan's experiments, the white eye allele in Drosophila was shown to be

Accepted Answer

A)  located on the X chromosome.
B)  located on the Y chromosome.
C)  dominant.
D)  located on an autosome.E) All of the above
F) None of the above

Question 3

Nondisjunction of a single pair of autosomes can lead to all of the following except

Accepted Answer

A)  aneuploidy.
B)  monosomy.
C)  trisomy.
D)  euploidy.E) A) and C)
F) All of the above

Question 4

Humans who have lost one copy of an autosome are called

Accepted Answer

A)  haploid.
B)  trisomic.
C)  bisomic.
D)  monosomic.E) B) and C)
F) All of the above

Question 5

Hemophilia is caused by a

Accepted Answer

A)  recessive allele on the X chromosome.
B)  dominant allele on the X chromosome.
C)  codominant allele on the X chromosome.
D)  recessive allele on an autosome.E) A) and C)
F) None of the above

Question 6

In sickle cell anemia, the defective hemoglobin differs from the normal hemoglobin by

Accepted Answer

A)  the color of the pigment.
B)  the size of the molecule.
C)  a single amino acid substitution.
D)  the total number of amino acids.E) A) and B)
F) C) and D)

Question 7

Why can't you use mitochondrial DNA to distinguish between these two suspects?

Accepted Answer

A)  The sequence of mitochondrial DNA has not yet been determined.
B)  The brothers share the same mitochondrial DNA.
C)  There are no molecular techniques available that allow one to analyze mitochondrial DNA.
D)  Because mitochondrial DNA is inherited in a paternal pattern.E) A) and D)
F) All of the above

Question 8

A genetic _____ indicates the distances between gene loci measured in terms of the frequency of recombination.

Accepted Answer

A)  map
B)  profile
C)  pedigree
D)  cloneE) C) and D)
F) A) and D)

Question 9

A human female with only one X chromosome is said to have a condition called

Accepted Answer

A)  X chromosome inactivation.
B)  Angelman syndrome.
C)  Turner syndrome.
D)  Klinefelter syndrome.E) B) and C)
F) A) and D)

Question 10

How many Barr bodies does a normal human female contain in each diploid cell?

Accepted Answer

A)  0
B)  1
C)  2
D)  3E) All of the above
F) B) and C) B

Question 11

In humans, if an XY individual had a deletion of the SYR gene, that person would

Accepted Answer

A)  develop as a female.
B)  have both male and female characteristics.
C)  have ambiguous genitalia.
D)  develop as a male.E) B) and C)
F) A) and B)

Question 12

The number of allele pairs that assort independently in an organism is generally much higher than the number of chromosome pairs.This phenomenon is due to

Accepted Answer

A)  independent assortment.
B)  segregation.
C)  crossing over.
D)  sex-linkage.E) A) and D)
F) B) and C) C

Question 13

What is the relationship between recombination frequency and the actual physical distance on a chromosome?

Accepted Answer

A)  As physical distance increases, the recombination frequency increases in a linear fashion.
B)  As physical distance increases, the recombination frequency decreases in a linear fashion.
C)  As physical distance increases, the recombination frequency first increases in a linear fashion, but gradually levels off to a frequency of 0.5.
D)  As physical distance increases, the recombination frequency first increases, but then decreases.E) C) and D)
F) None of the above

Question 14

Which statement about calico cats is false?

Accepted Answer

A)  Calico cats can be male or female.
B)  The different colored fur is due to the inactivation of one X chromosome.
C)  The variation in coat color is an example of an epistatic interaction.
D)  Calico cats are genetic mosaics.E) B) and C)
F) C) and D)

Question 15

If you needed to determine the order of genes on a chromosome, you should perform

Accepted Answer

A)  a test cross.
B)  a two-point cross.
C)  a three-point cross.
D)  a SNP test.E) None of the above
F) A) and B)

Question 16

Sickle cell anemia is caused by a defect in the

Accepted Answer

A)  oxygen-carrying pigment hemoglobin.
B)  ability of the blood to clot.
C)  ability of red blood cells to fight infection.
D)  chloride ion transport protein.E) A) and D)
F) B) and D)

Question 17

Occasionally, chromosomes fail to separate during meiosis, leading to daughter cells that have an abnormal number of chromosomes.This phenomenon is called

Accepted Answer

A)  epistasis.
B)  nondisjunction.
C)  crossing over.
D)  pleiotropy.E) None of the above
F) A) and D) B

Question 18

In humans, if non-disjunction led to an individual with a genotype of XO, that person would

Accepted Answer

A)  be female because each cell lacks a Y chromosome.
B)  be male because each cell has only one X chromosome.
C)  display both male and female characteristics.
D)  not survive.E) A) and B)
F) C) and D)

Question 19

Genetic exchange between 2 homologous chromosomes is called

Accepted Answer

A)  synapsis.
B)  pleiotropy.
C)  crossing over.
D)  allelic exchange.E) A) and C)
F) All of the above

Question 20

_______________ is a human hereditary disease that is caused by a dominant allele but does not show up in affected individuals until they are in middle age.

Accepted Answer

A)  Cystic fibrosis
B)  Sickle cell anemia
C)  Tay-Sachs disease
D)  Huntington's diseaseE) A) and B)
F) A) and C)

Exam 13: Chromosomes, Mapping, and the Meiosis-Inheritance Connection

Given that these two gene loci are very closely linked, the phenotypic ratio in the F2 generation should be closest to

Correct AnswerverifiedShow Answer

In Morgan's experiments, the white eye allele in Drosophila was shown to be

Correct AnswerverifiedShow Answer

Nondisjunction of a single pair of autosomes can lead to all of the following except

Correct AnswerverifiedShow Answer

Humans who have lost one copy of an autosome are called

Correct AnswerverifiedShow Answer

Hemophilia is caused by a

Correct AnswerverifiedShow Answer

In sickle cell anemia, the defective hemoglobin differs from the normal hemoglobin by

Correct AnswerverifiedShow Answer

Why can't you use mitochondrial DNA to distinguish between these two suspects?

Correct AnswerverifiedShow Answer

A genetic _____ indicates the distances between gene loci measured in terms of the frequency of recombination.

Correct AnswerverifiedShow Answer

A human female with only one X chromosome is said to have a condition called

Correct AnswerverifiedShow Answer

How many Barr bodies does a normal human female contain in each diploid cell?

Correct AnswerverifiedB

In humans, if an XY individual had a deletion of the SYR gene, that person would

Correct AnswerverifiedShow Answer

The number of allele pairs that assort independently in an organism is generally much higher than the number of chromosome pairs.This phenomenon is due to

Correct AnswerverifiedC

What is the relationship between recombination frequency and the actual physical distance on a chromosome?

Correct AnswerverifiedShow Answer

Which statement about calico cats is false?

Correct AnswerverifiedShow Answer

If you needed to determine the order of genes on a chromosome, you should perform

Correct AnswerverifiedShow Answer

Sickle cell anemia is caused by a defect in the

Correct AnswerverifiedShow Answer

Occasionally, chromosomes fail to separate during meiosis, leading to daughter cells that have an abnormal number of chromosomes.This phenomenon is called

Correct AnswerverifiedB

In humans, if non-disjunction led to an individual with a genotype of XO, that person would

Correct AnswerverifiedShow Answer

Genetic exchange between 2 homologous chromosomes is called

Correct AnswerverifiedShow Answer

_______________ is a human hereditary disease that is caused by a dominant allele but does not show up in affected individuals until they are in middle age.

Correct AnswerverifiedShow Answer

Given that these two gene loci are very closely linked, the phenotypic ratio in the F₂ generation should be closest to

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B

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C

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B

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