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Erythema migrans, a bull's-eye rash, at the site of a tick bite is associated with ______.


A) Lyme disease
B) Rocky Mountain spotted fever
C) Q fever
D) plague
E) ehrlichiosis

F) D) and E)
G) A) and D)

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The most important defense of the cardiovascular system against infection is ______.


A) the blood-brain barrier
B) lymph nodes
C) lymphocytes in the blood
D) fever

E) C) and D)
F) A) and D)

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Which of the following is not true of tularemia?


A) Its symptoms include fever, swollen lymph nodes, ulcerative lesions, conjunctivitis, and pneumonia.
B) The causative agent is a gram-positive bacterium.
C) It is transmitted by arthropod vectors.
D) It is sometimes called rabbit fever.
E) It is a zoonosis.

F) A) and B)
G) A) and C)

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The fibrous sac that encloses the heart is the ______.


A) myocardium
B) epicardium
C) ectocardium
D) endocardium
E) pericardium

F) C) and E)
G) None of the above

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At the blood donation facility, you are completing an information form. The form asks about your health history and includes a question about whether you have ever had malaria or visited a country where malaria is endemic. Why is this information relevant?


A) This is just one of many pathogens that blood is screened for. The information given by the donor saves the staff time in testing the blood.
B) Recipients differ in their susceptibility to malaria; if you have had malaria, the staff will earmark your blood to speci?c kinds of recipients.
C) Malarial parasites can persist in the liver, and, as a result, could be contaminating your blood and transferred to a recipient.
D) If you are infected with malaria, you are probably also infected with HIV, and that would disqualify your donation.

E) B) and C)
F) B) and D)

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Which of the following statements regarding erhlichiosis is incorrect?


A) Symptoms include fever, headache, and muscle pains.
B) The disease vector is transmitted by Ixodes ticks.
C) Treatment requires an extensive course of antibiotics, usually 3-6 weeks.
D) The disease is diagnosed by PCR or indirect fluorescent antibody tests.
E) It often coinfects with Borrelia burgdorferi.

F) C) and E)
G) B) and C)

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Retroviruses have all of the following characteristics except _______.


A) a DNA genome
B) integration into the host genome
C) reverse transcriptase
D) glycoprotein spikes
E) an envelope

F) None of the above
G) A) and D)

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Which type of hemorrhagic fever has been shown to respond to ribavirin?


A) Lassa fever
B) Rocky Mountain spotted fever
C) Ebola
D) Marburg

E) None of the above
F) All of the above

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Hemorrhagic and nonhemorrhagic fever diseases have a common feature of a high fever. These categories of diseases are distinguished by _______.


A) the pattern of the fever, whether it is constant or varies with time
B) viral causes in hemorrhagic fevers and bacterial or protozoan causes in nonhemorrhagic fevers
C) the viral load in the blood, specifically the viral titer
D) the integrity of the capillary endothelium and its ability to contain the blood
E) the overall mortality rate, as hemorrhagic fevers have a much higher mortality rate

F) B) and C)
G) C) and D)

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Under normal healthy circumstances, the lymphatic system filters any microorganisms present.

A) True
B) False

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Yersinia pestis _______.


A) was virulent historically but currently circulating strains are not virulent
B) is usually transmitted by a flea vector
C) has deer as an endemic reservoir
D) does not respond to antimicrobial drugs

E) A) and B)
F) None of the above

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When bacteria flourish and grow in the blood stream, the condition is termed ______.


A) fungemia
B) bactocarditis
C) sepsis
D) viremia

E) None of the above
F) C) and D)

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The reservoir for the Lassa fever virus is the ______.


A) Anopheles mosquito
B) multimammate rat
C) fruit bat
D) Aedes mosquito
E) deer tick

F) None of the above
G) A) and E)

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Which of the following statements regarding the Epstein-Barr virus is incorrect?


A) An infection typically requires hospitalization for about a week.
B) An infection results in sudden leukocytosis.
C) The virus is transmitted by direct oral contact and saliva.
D) The virus has a 30-50 day incubation period.
E) Transmission has been documented through contaminated blood transfusions and organ transplants.

F) D) and E)
G) A) and E)

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Following unprotected sex with a guy you met at a party, you are now worried about what you might have been exposed to during this episode. Ten days later, you talk to your doctor about getting an HIV test. What is the doctor's response?


A) The incidence of HIV infection in the United States is at an all-time low level, so transmission was not at all likely, especially after only a single possible exposure.
B) The antibiotic that you have been taking for a urinary tract infection will also destroy HIV, so you don't have to worry about an infection.
C) HIV infection can be latent and asymptomatic for years, so testing should be postponed until you exhibit symptoms of AIDS.
D) It's too soon to detect the antibody produced by your immune system in response to HIV exposure, so a test will come back negative. Wait a few more weeks to be tested.

E) A) and C)
F) A) and D)

Correct Answer

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Which of the following statements regarding Q fever is incorrect?


A) The causative agent, Coxiella burnetii, is transmitted by lice.
B) The disease is mild, and most cases go undetected.
C) The causative agent, Coxiella burnetii, produces resistant endospore-like structures.
D) Symptoms include fever, muscle aches, rash, and occasionally pneumonia.
E) Humans can be infected from the airborne spread of particles from infected animals.

F) B) and E)
G) A) and C)

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Epidemiologists classify diseases by their mortality rate (the percent of infected individuals who die from the disease) and by their communicability (how easy it is to transmit the disease) . Which of the following diseases of the cardiovascular system is mismatched with a description of its properties?


A) Plague; somewhat high mortality rate and low communicability
B) AIDS; high mortality rate and low communicability
C) Ebola; high mortality rate and high communicability
D) Malaria; low mortality rate and high communicability

E) B) and D)
F) A) and D)

Correct Answer

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The white-footed mouse, deer, and deer ticks are important to maintaining the zoonotic transmission cycle associated with ______.


A) plague
B) Rocky Mountain spotted fever
C) babesiosis
D) Lyme disease
E) Q fever

F) C) and E)
G) B) and C)

Correct Answer

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Which of these diseases would most likely be identified by viewing a stained blood smear in a light microscope?


A) HIV
B) Chagas disease
C) Dengue fever
D) Ebola hemorrhagic fever

E) None of the above
F) A) and B)

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Anthrax is not routinely diagnosed in the United States because _______.


A) healthcare workers haven't been trained to detect it
B) infections are usually asymptomatic
C) infection is generally only seen in late-stage AIDS patients
D) it is a rare infection

E) A) and B)
F) A) and C)

Correct Answer

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