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Spongiform encephalopathies are _______.


A) associated with abnormal, transmissible, protein in the brain
B) chronic, fatal infections of the nervous system
C) caused by prions
D) Creutzfeldt-Jacob disease, kuru, and Gertsmann-Straussler-Scheinker syndrome
E) All of the choices are correct.

F) All of the above
G) None of the above

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Cryptococcal meningitis is highly communicable among humans.

A) True
B) False

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Place the following components of the nervous system anatomy in order from skull to brain.


A) Pia mater, arachnoid mater, subarachnoid space, dura mater
B) Dura mater, arachnoid mater, pia mater, subarachnoid space
C) Dura mater, arachnoid mater, subarachnoid space, pia mater
D) Arachnoid mater, subarachnoid space, dura mater, pia mater
E) Subarachnoid space, arachnoid mater, dura mater, pia mater

F) A) and D)
G) A) and C)

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As a nurse, you have to teach your patients about control and management of their diseases as well as the facts of the disease--risk, treatment, symptoms, etc. How might you instruct a patient who hasWest Nile virus to avoid the infectious agent in the future?


A) Always drink bottled water when outside of the United States.
B) Do not eat food served from kiosks and food trucks in foreign countries.
C) Do not go outside at dusk or dawn, and cover the skin if this is unavoidable.
D) Get an annual vaccination if you live in an area where the virus is known to circulate.
E) Be sure to treat your dogs and cats with ?ea medication.

F) None of the above
G) All of the above

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Encephalitis caused by arboviruses involves the development of _______.


A) fever, headache, and rash
B) coma, convulsions, and paralysis in severe cases
C) myalgia and orbital pain
D) muscle aches and joint stiffness
E) All of the choices are correct.

F) D) and E)
G) A) and E)

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Your friend was bitten by an aggressive dog with a history of biting without cause, and it is suspected to have rabies. The city health department recommends the rabies vaccination, even though she has already been exposed to the infectious agent. Which statement best describes why the vaccine can be given post-exposure?


A) The virus exhibits a long incubation period, and therefore, in many cases, this provides the vaccine adequate time to have a protective effect in the patient.
B) This particular strain of the rabies virus is probably nonpathogenic, so the vaccine is given to boost the immune system's protective functions.
C) Since there is no treatment available, they suggest the vaccine as a last resort.
D) There were few virus particles in the bite, so her immune system has enough time to respond.

E) None of the above
F) A) and C)

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What do all of these diseases -- amoebic encephalitis, rabies, Creutzfeld-Jacob disease -- have in common?


A) They are all transmitted through animal bites.
B) Mortaility rates are all extremely high.
C) There is a genetic component to all of these diseases, in addition to the infectious agent.
D) They are all caused by protozoans.

E) B) and C)
F) None of the above

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Infectious diseases of the nervous system include those that affect the meninges only (meningitis) , those that affect both the meninges and the brain (meningoencephalitis) , and those that affect the brain only (encephalitis) . From the list below, identify the disease and its classi?cation that is Mismatched.


A) La Crosse Virus infection - encephalitis
B) Naegleria fowleri infection - meningoencephalitis
C) Valley Fever - meningitis
D) African sleeping sickness - encephalitis
E) Polio - meningitis

F) C) and E)
G) D) and E)

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Which of the following is caused by Haemophilus in?uenzae?


A) Tetanus
B) In?uenza (?u)
C) Kuru
D) Bacterial meningitis
E) Pharyngitis

F) All of the above
G) A) and B)

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Botox injections contain botulinum toxin.

A) True
B) False

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The expected outcome of an oxidase test performed to identify Neisseria menigitidis is _______.


A) cells colored black when stained and viewed under the microscope
B) a zone of clearing surrounding colonies on chocolate agar
C) the appearance of bubbles when cells are mixed with hydrogen peroxide
D) a color change of a colony from tan to black when oxidase reagent is added
E) the amplification of the oxi gene as detected on an agarose gel

F) C) and D)
G) A) and D)

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Toxoplasmosis prevention includes ______.


A) vaccination of cats
B) hygienic precautions
C) vaccination of humans
D) vector control

E) B) and D)
F) A) and D)

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Which of the following is/are a sign or symptom of meningitis?


A) Headache
B) Stiff neck
C) White blood cells in cerebrospinal fluid
D) Fever
E) All of the choices are correct.

F) B) and E)
G) C) and D)

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Treatment for Neisseria meningitidis consists of ______.


A) oral penicillin G
B) tetracycline
C) intravenous penicillin G
D) vancomycin
E) rifampin

F) C) and D)
G) A) and E)

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Meningitis can be caused by a number of microbes, and the causative organism is often identi?ed by microscopic observation of the cerebrospinal ?uid. Identify the mismatch in the following list of organisms and the description of the microscopic observation.


A) Neisseria meningitidis; gram-negative diplococcus
B) Streptococcus pneumoniae; gram-positive ?attened coccus
C) Cryptococcus neoformans; fungal cells with a thick capsule
D) Listeria monocytogenes; gram-negative coccobacillus with ?agella
E) Enterovirus; no bacteria appear to be present in CSF

F) B) and D)
G) C) and D)

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Neisseria meningitidis is transmitted by ______.


A) an insect vector
B) close contact
C) fomites
D) sexual contact

E) A) and B)
F) All of the above

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The oral and inactivated polio vaccines are made from plant cell cultures.

A) True
B) False

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Which of the following statements is incorrect regarding Listeria monocytogenes?


A) It is resistant to salt
B) It is fastidious
C) It is resistant to heat
D) It is resistant to cold
E) It does not produce a capsule

F) B) and E)
G) A) and B)

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A group of men make an annual week-long hunting trip for deer season in West Virginia. This year, they had to chase a family of squirrels out of the cabin, and during the week, they killed several deer and processed the meat, eating venison steaks most nights. All of the men had a few mosquito bites, and two cases of beer were consumed. The following week, they all developed symptoms of fever, headache, confusion, and seizures. Which of the following organisms can be ruled out as the cause of this encephalitis?


A) Powassan Virus
B) JC Virus
C) Jamestown Canyon Virus
D) Eastern Equine Encephalitis Virus

E) A) and B)
F) All of the above

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Subacute encephalitis may be caused by ______.


A) Toxoplasma gondii
B) prions
C) herpes simplex virus
D) persistent measles virus
E) All of the choices are correct.

F) B) and C)
G) C) and D)

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