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Which of the following is not a virulence factor associated with helminths?


A) Degradative enzymes to damage host tissue
B) Specialized structures for attachment to host tissues
C) Secretion of toxins
D) Thick cuticle to escape detection from the host immune system

E) None of the above
F) C) and D)

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General symptoms of helminth infection includes all of the following except


A) eggs, larvae, or adult worms found in feces.
B) intense abdominal pain.
C) increased eosinophil count.
D) vague nausea.
E) increased sensitivity to helminth antigens.

F) None of the above
G) B) and E)

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Which of the following attributes is not common to the life and transmission cycles of Opisthorchis sinensis,Clonorchis sinensis,and Fasciola hepatica?


A) Infection causes obstruction of the bile duct.
B) Eggs are released in the feces.
C) They are transmitted by consuming inadequately cooked fish.
D) Fresh water snails are an intermediate host.

E) B) and D)
F) None of the above

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Which of the following statements is not true regarding Clostridium difficile?


A) Infection is precipitated by broad-spectrum antibiotic therapy.
B) It produces "rice-water" stools.
C) It is part of the normal intestinal biota.
D) It is also called pseudomembranous colitis.
E) It is a gram-positive, endospore-forming rod.

F) A) and E)
G) B) and C)

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Which of the following statements regarding fecal transplant is correct?


A) Donors and recipients must be carefully matched to prevent an immune reaction in the recipient.
B) The goal is to completely eradicate Clostridium difficile from a patient's gut microbiota and replace it with a healthy community.
C) Fecal matter must be carefully disinfected and screened for viruses, cysts, and endospores before transfer to a recipient patient.
D) This treatment is designed to jump-start the intestinal microbiota after an infection with Clostridium difficile resuts in acute diarrhea.

E) A) and D)
F) A) and C)

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Because the gut microbiome is a tremendously diverse population,an infection can be viewed as


A) the presence of helminths instead of the normal bacteria in the gut.
B) an increase in the overall number of microbes in the gut.
C) a shift in the relative proportions of the microbes in this environment.
D) a change in a person's enterotype.

E) C) and D)
F) All of the above

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Which of the following statements regarding schistosomiasis is incorrect?


A) There is only a single drug available to treat Schistosoma infection, praziquantel, and drug-resistant strains are beginning to arise.
B) Once a person has recovered from an infection with Schistosoma mansoni, they are protected with lifelong immunity.
C) Efficacy of treatment is assess by observing fecal samples placed in water for whether eggs can hatch to release live miracidia.
D) Schistosomiasis is transmitted by exposing the skin to a water source that has been contaminated with sewage.

E) A) and B)
F) B) and D)

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Research does not indicate a link between the numbers and types of bacteria causing periodontitis and thicker carotid arteries in an individual.

A) True
B) False

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Which of the following statements is incorrect about Staphylococcus aureus food intoxication?


A) Food left unrefrigerated for several hours is at risk for contamination.
B) Symptoms come on quickly and include nausea, vomiting, and diarrhea.
C) Food becomes contaminated by a human carrier.
D) Common affected foods include custards, ham, cream pastries, and processed meats.
E) Ingestion of the pathogen allows it to multiply and damage the GI tract lining.

F) B) and E)
G) D) and E)

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Giardiasis involves


A) a protozoan that does not form cysts.
B) infection of the large intestine.
C) symptoms of abdominal pain, flatulence, and diarrhea.
D) vector transmission.
E) All of the choices are correct.

F) A) and D)
G) None of the above

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A current news story describes a cruise ship in the Carribbean with an outbreak of diarrheal illness,affecting hundreds of people.With all of those people in a small area,opening and closing doors,using handrails,etc,you are trying to figure out what infectious agent may be the cause.Your most likely guess is that the pathogen is ______.


A) Clostridium difficile
B) hepatitis B
C) norovirus
D) cholera
E) shiga-toxin-producing E.coli

F) B) and E)
G) All of the above

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Which of the following is not a helminth that causes primarily intestinal symptoms?


A) Taenia solium
B) Diphyllobothrium latum
C) Trichuris trichiura
D) Enterobius vermicularis

E) B) and C)
F) A) and C)

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Only feces from humans that contaminates food and water can be involved in transmission of amoebiasis.

A) True
B) False

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Identify the mismatch in the following list of helminths and their common names.


A) Schistosoma mansoni; blood fluke
B) Ascaris lumbricoides; intestinal roundworm
C) Opisthorchis sinensis; liver fluke
D) Trichuris trichiura; whipworm
E) Taenia solium; pinworm

F) B) and D)
G) B) and C)

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Vibrio cholerae can be readily isolated and identified in the laboratory from stool samples by


A) dark-field microscopy looking for motility.
B) its ability to grow at high temperature and produce zones of clearing on blood agar.
C) its robust chemotactic response to the presence of chitin.
D) growth on selective media followed by PCR of its 16S rRNA gene.

E) B) and C)
F) A) and D)

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The most definitive test to diagnose a helminth infection is


A) a blood cell count to look for elevated levels of eosinophils.
B) a good medical history of the patient, including recent foreign travel.
C) an ova and parasite smear for microscopy.
D) a serological test for the presence of anti-helminthic antibodies.

E) B) and C)
F) All of the above

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Enteropathogenic E. coli (EPEC) causes gut effacement with shiga toxin.

A) True
B) False

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Salmonella are ______.


A) methane producers
B) motile
C) gram-positive bacilli
D) lactose fermenters
E) All of the choices are correct.

F) All of the above
G) C) and D)

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Which of the following statements regarding Campylobacter infection is incorrect?


A) It can lead to Guillain-Barre syndrome.
B) It is caused by a shiga toxin.
C) Campylobacter burrows into the mucosa of the ileum and multiplies.
D) It can last over 2 weeks.
E) It can cause acute temporary paralysis.

F) A) and E)
G) A) and B)

Correct Answer

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All of the following are true of acute necrotizing ulcerative gingivitis (ANUG) except that it


A) is common in AIDS patients.
B) is associated with severe pain, bleeding, pseudomembranes, and necrosis.
C) involves Treponema vincentii, Prevotella intermedia, and Fusobacterium.
D) is due to poor oral hygiene, altered host defenses, or prior gum disease.
E) is highly contagious.

F) B) and E)
G) A) and E)

Correct Answer

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