Question 1

Plasma cells

Accepted Answer

A)  secrete antibodies.
B)  function in allergic reactions.
C)  directly destroy target cells.
D)  suppress immune reactions.
E)  activate B cells and other T cells.F) C) and D)
G) A) and B)

Question 2

All of the following are characteristics of IgM except

Accepted Answer

A)  has 10 antigen binding sites.
B)  contains a central J chain.
C)  is the first class synthesized by a plasma cell.
D)  can serve as a B-cell receptor.
E)  is a dimer.F) C) and D)
G) All of the above

Question 3

Destruction of lymphocytes with self-specificity is called

Accepted Answer

A)  clonal deletion.
B)  proliferation.
C)  clonal selection.
D)  differentiation.
E)  hypersensitivity.F) A) and D)
G) All of the above

Question 4

Class I MHC genes code for

Accepted Answer

A)  certain secreted complement components.
B)  self receptors recognized by T lymphocytes.
C)  all HLA antigens.
D)  receptors located primarily on macrophages and B cells.E) A) and D)
F) All of the above

Question 5

The monomer subunit of immunoglobulin molecules has all of the following except

Accepted Answer

A)  two identical heavy polypeptide chains.
B)  two identical light polypeptide chains.
C)  disulfide bonds between polypeptide chains.
D)  four antigen binding sites.
E)  a variable and constant region on each polypeptide chain.F) B) and E)
G) A) and C)

Question 6

Cytotoxic T cells

Accepted Answer

A)  are activated by free,soluble antigens.
B)  lack specificity for antigen.
C)  secrete granzymes and perforins that damage target cells.
D)  secrete interleukin-2 to stimulate B and T cells.E) A) and C)
F) A) and B)

Question 7

Superantigens are

Accepted Answer

A)  body tissues that the immune system mistakes as foreign.
B)  cell markers found in some member of a species but not in other members.
C)  bacterial toxins that activate T cells at a 100 times greater rate than other antigens.
D)  antigens that evoke allergic reactions.E) A) and C)
F) A) and D)

Question 8

The array of potential antibodies to the variety of possible antigens is amazing.Which statement explains this development?

Accepted Answer

A)  Recombination of hundreds of genes for antigen receptors occurs during the developmental stage of lymphocyte production.
B)  Mutations in the antibody gene occur within the activated B cells,since they meet the antigen.
C)  There is a shuffling of genes that code for self markers as well as nonself markers,mixing them together and producing reactive lymphocytes to those markers.
D)  The existing antibody molecules change their shapes,allowing them to fit with a large number of antigens.E) A) and B)
F) A) and D)

Question 9

The antibody-secreting progeny cells of a B-cell clone are called

Accepted Answer

A)  antibodies.
B)  sensitized T cells.
C)  activated macrophages.
D)  plasma cells.
E)  bursa cells.F) A) and C)
G) C) and D)

Question 10

The secondary response to an antigen is more rapid and robust than the primary response.

Accepted Answer

A) True 
 B)False

Question 11

An example of artificial active immunity would be

Accepted Answer

A)  chickenpox infection,followed by lifelong immunity.
B)  chickenpox vaccine triggering extended immunity to chickenpox.
C)  giving a person immune serum globulins to chickenpox virus after exposure to the disease.
D)  a fetus acquiring maternal IgG to the chickenpox virus across the placenta.E) B) and C)
F) C) and D)

Question 12

The region of each antibody molecule where amino acid composition is highly diversified from one clone of B lymphocytes to another is the _____ region.

Accepted Answer

A)  variable
B)  joining
C)  constant
D)  light
E)  hingeF) A) and D)
G) C) and D)

Question 13

Specific immunity provides long-lasting protection through the production of ____.

Accepted Answer

A)  antibodies
B)  plasma cells
C)  T helper cells
D)  memory cells
E)  phagocytotic cellsF) D) and E)
G) All of the above

Question 14

What process generates many B cells and T cells that are activated against specific antigens?

Accepted Answer

A)  antigen expression
B)  antibody production
C)  clonal expansion
D)  antigen presentation
E)  opsonizationF) D) and E)
G) C) and D)

Question 15

Human B lymphocytes mature in an intestinal region called the bursa.

Accepted Answer

A) True 
 B)False

Question 16

Small foreign molecules that are too small by themselves to elicit an immune response are termed

Accepted Answer

A)  epitopes.
B)  haptens.
C)  antigen binding sites.
D)  variable regions.E) All of the above
F) C) and D)

Question 17

Which is incorrect about the Fc region of an immunoglobulin?

Accepted Answer

A)  is called the crystallizable fragment
B)  forms the antigen binding sites
C)  contains an effector molecule that can bind to cells such as macrophages and mast cells
D)  contains an effector molecule that can fix complement
E)  determines the class to which the immunoglobulin belongsF) All of the above
G) B) and D)

Question 18

Which of the following is not a property of B cells?

Accepted Answer

A)  produce plasma cells and memory cells
B)  low numbers circulating in the blood
C)  require antigen presented with MHC proteins
D)  receptors called immunoglobins
E)  mature in the bone marrowF) A) and C)
G) C) and E)

Question 19

Which process involves antibodies covering surface receptors on a virus or toxin molecule,thereby disrupting their activity?

Accepted Answer

A)  neutralization
B)  opsonization
C)  complement fixation
D)  agglutination
E)  anamnestic responseF) A) and E)
G) A) and D)

Question 20

During which response to the antigen do we display a latent period of no secretory antibody synthesis?

Accepted Answer

A)  primary
B)  secondary
C)  tertiary
D)  quaternaryE) A) and C)
F) C) and D)

Exam 15: Host Defenses II: Specific Immunity and Immunization

Cytotoxic T cells

Correct AnswerverifiedShow Answer

Small foreign molecules that are too small by themselves to elicit an immune response are termed

Correct AnswerverifiedShow Answer

The region of each antibody molecule where amino acid composition is highly diversified from one clone of B lymphocytes to another is the _____ region.

Correct AnswerverifiedShow Answer

Destruction of lymphocytes with self-specificity is called

Correct AnswerverifiedShow Answer

The array of potential antibodies to the variety of possible antigens is amazing.Which statement explains this development?

Correct AnswerverifiedShow Answer

Human B lymphocytes mature in an intestinal region called the bursa.

Correct AnswerverifiedShow Answer

The secondary response to an antigen is more rapid and robust than the primary response.

Correct AnswerverifiedShow Answer

What process generates many B cells and T cells that are activated against specific antigens?

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Which of the following is not a property of B cells?

Correct AnswerverifiedShow Answer

The antibody-secreting progeny cells of a B-cell clone are called

Correct AnswerverifiedShow Answer

The monomer subunit of immunoglobulin molecules has all of the following except

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Superantigens are

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An example of artificial active immunity would be

Correct AnswerverifiedShow Answer

Specific immunity provides long-lasting protection through the production of ____.

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Which is incorrect about the Fc region of an immunoglobulin?

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During which response to the antigen do we display a latent period of no secretory antibody synthesis?

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All of the following are characteristics of IgM except

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Plasma cells

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Which process involves antibodies covering surface receptors on a virus or toxin molecule,thereby disrupting their activity?

Correct AnswerverifiedShow Answer

Class I MHC genes code for

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